Endocrine Abstracts

The production and activities of steroid hormones during pregnancy have many interesting aspects. Their synthesis and metabolism are the result of complex metabolic pathways encompassing activities in the fetus, placenta, and mother. Progesterone, estrogens, androgens and glucocorticoids all play important roles during pregnancy, from implantation to delivery. Focusing on selected steroid hormones in the peripartum period, we defined reference ranges measured using LS-MS/MS, a...

Smoking has many effects on human health and reproduction. Women are generally recommended to quit smoking before conception. Cessation improves fertility and helps avoid many health risks for the mother and the child and plays an important role in the future development and health of the offspring. We have decided to perform a study following changes in the production of steroid hormones in pregnant smokers and ex-smokers compared to non-smokers. In physiological pregnancies,...

Objective: Smoking during pregnancy could have impact on steroidogenesis, with more marked changes in smokers carrying boys as well as in their newborns. The aim of study was compared steroid hormones between non-smokers, ex-smokers, which stop smoking in the beginning of pregnancy, and active smokers.Method: We focused on changes in steroidogenesis in the blood of mothers in their 37th week of pregnancy and in mixed cord blood from their newb...